SUID HERPESVIRUS 1 (AUJESZKY’S DISEASE VIRUS; PSEUDORABIES)

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Causative Agent(s)

Pseudorabies virus. It belongs to the Family Herpesviridae, Subfamily Alphaherpesvirinae and Genus Varicellovirus.

Clinical Presentation and Epidemiology

The disease is found everywhere in the world except Norway, Australia, and most of the islands Southeast Asia.

The clinical signs observes in infected pigs are fever, anorexia, vomiting, coughing, sneezing, dyspnea, profuse salivation, listlessness, trembling and incoordination.

Diagnostic Considerations

The samples required for viral isolation are serum, nasal swab, trigeminal and olfactory ganglia, tonsils, lungs, spleen, liver, kidneys, lymph nodes, and pharyngeal mucosa.

The laboratory examinations that are used diagnose this disease are virus isolation in conventional cell cultures utilizing a variety of cells, however porcine kidney cell line is preferred.

Other tests include enzyme-linked immunosorbent assays (ELISAs), immunoperoxidase, immunofluorescence and neutralization assays (requiring specific antisera), DNA hybridization dot-blot assay and Polymerase chain reaction (PCR).

Management and Treatment

There is no treatment for this disease.

Other approaches to reduce spread include vaccination with inactivated and modified live virus vaccines.