MYCOPLASMA SYNOVIAE INFECTION

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Causative Agents

Mycoplasma synoviae

Clinical Presentation and Epidemiology

Mycoplasma synoviae is egg transmitted (transovarian), but the infection rate in breeder hens is low.

The first signs of infectious synovitis include pale-bluish head parts and lameness in many birds with a tendency to sit. The more severely affected birds are depressed and found resting around feeders and waterers. Hocks and footpads are swollen, and sternal bursitis (breast blisters) may be seen.

Diagnostic Consideration

Presumptive diagnosis based on clinical signs and gross lesions should be confirmed by laboratory tests. Serum plate agglutination or Enzyme Linked Immunosorbent Assay are used to detect M synoviae antibodies, but cross-reactions with M gallisepticum and other nonspecific reactions may occur. Polymerase Chain Reaction may be used to rapidly detect M synoviae DNA from pre- or post-mortem specimens.

Management and Treatment

Oxytetracycline or chlortetracycline at 200 g/ton feed for 5 to 7 days. Tylosin has been injected subcutaneously at 1.3-2.2 mg/kg body weight or administered at 0.5-0.75 g/l drinking water for 3-5 days.